With looming uncertainties and disruptions in today’s global supply chains, such as lockdown measures to contain COVID-19, supply chain resilience has gained considerable attention recently. While decision-makers in procurement have emphasized the importance of traditional risk assessment, its shortcomings can be complemented by resilience. However, while most resilience studies are too qualitative in nature and abstract to inform supplier decisions, many quantitative resilience studies frequently rely on complex and impractical operations research models fed with simulated supplier data. Thus there is the need for an integrative, intermediate way for the practical and automated prediction of resilience with real-world data. We therefore propose a random forest-based supervised learning method to predict supplier resilience, outperforming the current human benchmark evaluation by 139 percent. The model is trained on both internal ERP data and publicly available secondary data to help assess suppliers in a pre-screening step, before deciding which supplier to select for a speciﬁc product. The results of this study are to be integrated into a software tool developed for measuring and tracking the total cost of supply chain resilience from the perspective of purchasing decisions.